HAPPY HOLIDAYS EVERYONE!! ENJOY THE HOLIDAY BREAK :)


Agenda:

• Meets/Exceeds Test Prep Unit 2
• NEW TEST DATE NEXT WEDNESDAY DECEMBER 14th 
• Ms. Lakeman's Test Prep Links Click Here

Meets Links:
Question 1: Molecular Techniques for PTC lab: http://bioinformatics.dnalc.org/ptc/animation/ptc.swf


Question 2: Molecular logic of screening your PTC genes
http://bioinformatics.dnalc.org/ptc/animation/ptc.swf
(please click on results and discussions)


Question 3: Genetic Disorders
CHROMOSOMAL: For Turner, Down, Klinefelter, or Williams syndromes click here: 
http://learn.genetics.utah.edu/content/disorders/chromosomal/

FOR SINGLE GENE Cystic Fibrosis, Maple Syrup Urine Disease, Huntington's Disease Click here: 

http://learn.genetics.utah.edu/content/disorders/singlegene/

Question 4: Gene delivery tools- the following can be on the test: Retroviruses, Adenovirus, Adeno-associated virus, 

http://learn.genetics.utah.edu/content/genetherapy/tools/

Exceeds Link:

1. PCR Amplification:

PCR OVERVIEW http://learn.genetics.utah.edu/content/labs/pcr/
PCR CYCLE: http://www.sumanasinc.com/webcontent/animations/content/pcr.html

2. CRISPR Technology

Great overview: yourgenome.org 

Straight forward explanation: infographic (you get some points)

Comprehensive review: click on this infographic (you get more points for this type of explanation)

3. Molecular logic of of bitter taste perception.

http://learn.genetics.utah.edu/content/basics/ptc/

4. Amniocentesis and CVS:

Amniocentisis animation: 

http://www.cengage.com/biology/discipline_content/animations/amniocentesis_m.html

Amnio vs. CVS:

http://images.slideplayer.com/7/1738899/slides/slide_15.jpg

https://geneticcounseling.info/

Start Activity 2.2.1: Gene Therapy

Using Viruses to cure cancer:
http://www.abc2news.com/newsy/were-slowly-recruiting-viruses-to-treat-cancer
http://www.nbcnews.com/watch/nbc-news-channel/doctors-cure-womens-cancer-with-polio-injection-242736707676

Can we live forever:  http://video.pbs.org/video/1754457671/

Part I: Mechanics of Gene Therapy

1. Visit the Genetic Science Learning Center (GSLC) Gene Therapy site

 (Links to an external site.) and read the three sections listed below.

• What is Gene Therapy?
• Choosing Targets for Gene Therapy
• Gene Delivery: The Key to Gene Therapy

3. Use your Student Response Sheet to complete the GSLC Space Doctor interactive found at   http://learn.genetics.utah.edu/content/genetherapy/doctor/ 

 (Links to an external site.)

Part II: Debating Gene Therapy:  

Against the use of gene therapy.

• The New York Times – Patient Dies During a Trial of Therapy Using Geneshttp://query.nytimes.com/gst/fullpage.html?sec=health&res=9E06EED8173EF93AA1575AC0A96F958260 (Links to an external site.)
• Fox News – Boy Living in Bubble Develops Leukemia From Experimental Therapyhttp://www.foxnews.com/story/0,2933,317225,00.html (Links to an external site.)
• BBC News Magazine – Gene Doping: Sport’s Biggest Battle?http://www.bbc.com/news/magazine-25687002 (Links to an external site.)  
• The New York Times – 2nd Cancer is Attributed to Gene Used in FDA Testhttp://query.nytimes.com/gst/fullpage.html?res=9801E7DB1F31F934A25752C0A9659C8B63 (Links to an external site.)
• ABC News – Patient Death Latest Setback for Gene Therapyhttp://abcnews.go.com/Health/Story?id=3421869&page=1 (Links to an external site.)
• The New York Times – Trials are Halted on a Gene Therapyhttp://query.nytimes.com/gst/fullpage.html?res=9C01E7D9163BF937A35753C1A9649C8B63 (Links to an external site.)

In favor of gene therapy: 

• Biology News Net – Gene Therapy Shows Promise as Weapon Against HIVhttp://www.biologynews.net/archives/2009/02/23/gene_therapy_shows_promise_as_weapon_against_hiv.html (Links to an external site.)
• New Scientist - Gene Therapy Cures “Bubble Boy”http://www.newscientist.com/article/dn2124-gene-therapy-cures-bubble-boy.html (Links to an external site.)
• The New York Times – More Than Humanhttp://www.nytimes.com/2005/07/03/books/chapters/0703-1st-naam.html (Links to an external site.)
• New Scientist – Gene Therapy is First Deafness ‘Cure’http://www.newscientist.com/article/dn7003 (Links to an external site.)
• Stanford University Medical Center – Gene Therapy for Muscular Dystrophy Fixes Frail Muscle Cells in Animal Model http://www.eurekalert.org/pub_releases/2005-12/sumc-gtf122205.php (Links to an external site.)
• USA Today – Gene Therapy Experiments Improve Vision in Nearly Blindhttp://www.usatoday.com/tech/science/2008-04-28-3714044875_x.htm (Links to an external site.)

Nov. 28 2016

Agenda:

• Activity 2.2.2: Reproductive Technology and Genetic Engineering
• Radiolab: CRISPR Technology
• MIT & CRISPR Video

Part 2: Resource Links for learning about CRISPR:

• The website on yourgenome.org provides the most information

• Nature magazine's infographic is straightforward and great

• Know your Neurons infographic goes deeper and more comprehensive

• The video on Vimeo is also very helpful for modifying and mutating genes using CRISPR

Part 3: 

• View the ArgosBiotech’s website, Cloning: A Timeline

• View University of Utah's website on what is cloning?

• Nation Human Genome Research Institute - Cloning fact sheet 

Learning Target(s)

I can ...

• analyze various perspectives on reproductive technologies and genetic engineering tools like CRISPR.

• demonstrate and model how the CRISPR system works to genetically alter DNA.  

Nov. 21st, 2016

Agenda:

Activity 2.1.5 Maternal and Child Health

Abnormal Karyotypes:  http://learn.genetics.utah.edu/content/disorders/chromosomal/

Part I: Prenatal Screening: Amniocentesis and Chorionic Villus Sampling (CVS)

• American Pregnancy Association – Amniocentesis http://www.americanpregnancy.org/prenataltesting/amniocentesis.html (Links to an external site.)
• American Pregnancy Association – Chorionic villus sampling http://www.americanpregnancy.org/prenataltesting/cvs.html (Links to an external site.)

 Part II: Prenatal Monitoring: Ultrasound

 View the video clip on ultrasound listed below:

Mayo Clinic: Fetal Ultrasound http://www.mayoclinic.com/health/ultrasound/MM00084 (Links to an external site.)


12. Research what can be learned about a fetus by looking at an ultrasound image by reading the information presented on Obstetric Ultrasound Scans at:  http://www.ob-ultrasound.net/

 (Links to an external site.)14. Read the National Geographic article 4-D Ultrasound Gives Video View of Fetuses in the Womb: http://news.nationalgeographic.com/news/2005/02/0225_050225_tv_ultrasound.html

 (Links to an external site.)15. Explore the 4D Ultrasound Scan Video Clips presented by Dr. Najeeb Layyous found at http://www.layyous.com/ultasound/ultrasound_video.htm

 (Links to an external site.)

Points

None

Submitting

Nothing

Week of October 31st, 2016

Agenda:

• Activity 2.1.2 Copying our Genes
• https://docs.google.com/presentation/d/1lxoNVzSx8abFp2HYSym3XY5RCArbi5X0DHLlg5h2JTU/edit?usp=sharing

Part I: How PCR Works:

• PCR OVERVIEW http://learn.genetics.utah.edu/content/labs/pcr/
• PCR CYCLE: http://www.sumanasinc.com/webcontent/animations/content/pcr.html
• PCR CYCLE: https://www.thermofisher.com/us/en/home/life-science/pcr/elevate-pcr-research/pcr-video-library/pcr-animation.html

Part 2:  Overview of your lab tomorrow: Use the link to answer the questions.

• http://bioinformatics.dnalc.org/ptc/animation/ptc.swf

Part 3: Learn about tasting bitterness: 

• http://learn.genetics.utah.edu/content/basics/ptc