Date: December 15th,

Agenda:

• Activity 3.1.6: When cells lose control
• Immuno-staining wild type and cancer cells

Part I: Normal Cells Versus Cancer Cells

1. Obtain a Student Response Sheet from the teacher.

2. Answer Questions 1-4 on the Student Response Sheet as you watch the video “Cancer and the Cell Cycle” found at Emory University’s CancerQuest 

website: http://www.cancerquest.org/images/FLV/fullDocumentary/English/fullDocInterfaceEng.swf (Links to an external site.)

3. Brainstorm how you think mutations occur in proto-oncogenes and tumor suppressor genes that can lead to cancer.

4. Investigate how a proto-oncogene becomes an oncogene as you view the Annenberg Media’s animation “How a Proto-oncogene Becomes an Oncogene” found at: http://www.learner.org/courses/biology/archive/animations/hires/a_cancer2_h.html (Links to an external site.)

    Another Resource Link: http://www.hhmi.org/biointeractive/p53-gene-and-cancer

5. Answer question 5 on the Student Response Sheet.

6. Answer Question 6 on the Student Response Sheet as you watch the Annenberg Media’s animation “p53’s Role in the Cell” about how one particular tumor suppressor gene works, found at:http://www.learner.org/courses/biology/archive/animations/hires/a_cancer3_h.html (Links to an external site.)                      Another Resource Link: http://www.hhmi.org/biointeractive/p53-gene-and-cancer

Learning Targets:

I can ...

• compare and contrast cellular and molecular mechanisms of normal cells and cancer cells. 
• implement advanced molecular techniques to stain normal cells and cancer cells to study under my microscope.

December 9th

Agenda:
Meets/Exceeds Exam Prep
Avid will come next Tuesday to see our class


Meets Resource Links:

Question 1: PCR
http://learn.genetics.utah.edu/content/labs/pcr/


Question 2: Restriction enzyme HAE III works
http://bioinformatics.dnalc.org/ptc/animation/ptc.swf


Question 3: Genetic Disorders:
MDA Organization: https://www.mda.org/disease/duchenne-muscular dystrophy/overview

DMD: http://www.sciencedaily.com/releases/2015/10/151022141722.htm  

Cystic Fibrosis: http://learn.genetics.utah.edu/content/disorders/singlegene/cf/

Huntington's Disease:: http://hdsa.org/what-is-hd/

Down Syndrome:  http://www.ndss.org/Down-Syndrome/
Alzheimer's Disease:  http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp
Leber Hereditary optic neuropathy:  http://lhon.org/lhon/LHON_101.html

Question 4: Genetic engineering using vectors
http://learn.genetics.utah.edu/content/tech/genetherapy/


Exceeds Resource Links
Question 1:
DNA Microarray:  http://learn.genetics.utah.edu/content/labs/microarray/

Question 2: 
CRISPR Video: http://blog.openhelix.eu/?p=20308
CRISPR Diagram:  http://www.the-scientist.com/images/

Question 3:
Taste Perception: http://learn.genetics.utah.edu/content/inheritance/ptc/

Question 4: 
Amniocentesis and CVS: http://familydoctor.org/familydoctor
Amniocentesis Video: http://www.stanfordchildrens.org/en/topic/
CVS animation: http://www.cengage.com/biology/

Agenda: 3.1.4: When Cells Lab

DNA Microarray Virtual Lab

1. Obtain a Student Response Sheet from your teacher.

2. Go to the “DNA Microarray Virtual Lab” found at the University of Utah’s Learn.Genetics: Genetic Science Learning Center’s website:  http://learn.genetics.utah.edu/content/labs/microarray/ (Links to an external site.)

3. Click on the picture of the microarray to begin.

4. Click on “Chapter 3: The Experiment!” to begin the virtual experiment.

5. Answer the questions on your Student Response Sheet as you work through the virtual DNA microarray experiment.

6. Answer Conclusion questions 1 – 3.

Agenda: 

3.2.1: Lessons from a Fly

Resources:

Male/Female:
http://www.wikihow.com/Distinguish-Between-Male-and-Female-Fruit-Flies

Life Cycle:
http://skenderianscience.weebly.com/uploads/2/6/1/4/26143564/7822724_orig.jpg

Fly Fight Club: 
http://www.hms.harvard.edu/bss/neuro/kravitz/

Agenda: December 1st, 2015

Activity 3.13a: Hormones gone wild

BBC Two: Hormones and the brain

Resources Online Links:

• Nemours Foundation- A Body Basics Article: Endocrine Systemhttp://kidshealth.org/teen/your_body/body_basics/endocrine.html (Links to an external site.)
• The Hormone Foundation – Endo 101: Endocrine Glandshttp://www.hormone.org/Endo101/page2.cfm (Links to an external site.)
• Medline Plus – Medical Dictionary: Hormoneshttp://www.nlm.nih.gov/medlineplus/hormones.html (Links to an external site.)
• Tour of the Endocrine System http://www.innerbody.com/image/endoov.html (Links to an external site.)
• Biology at University of Cincinnati Clermont College: Endocrine Systemhttp://www.biology.clc.uc.edu/courses/bio105/endocrin.htm (Links to an external site.)