Activity 3.4.1 Personalized Medicine
Feb. 28th, 2018
Agenda:
Agenda:
- Activity 4.3.1 Personalized Medicine
- TPMT VIDEO http://learn.genetics.utah.edu/content/precision/example/
- Nell's DNA sequence
Resources:
Bioserver:
SNPs make sense:
What is Acute Lymphoblastic Leukemia (ALL):
https://medcomic.com/medcomic/acute-lymphoblastic-leukemia/https://www.cancer.gov/types/leukemia/patient/child-all-treatment-pdq
PLTW Cancer Center – Bioinformatics Lab
DNA Sequence Data: partial TPMT gene (840 base pairs) – acute lymphoblastic leukemia (ALL) patients
Renee
gcgggcggag gcggggcgcg gagaagtggc ggaggtggaa gcggaggcgt acccgcccct
ggggacgtca ttggtggcgg aggcaatggc cggcaaccag ctgtaagcga ggcacggaag
acatatgctt gtgagacaaa ggtgtctctg aaactatgga tggtacaaga acttcacttg
acattgaaga gtactcggat actgaggtac agaaaaacca agtactaact ctggaagaat
ggcaagacaa gtgggtgaac ggcaagactg cttttcatca ggaacaagga catcagctat
taaagaagca tttagatact ttccttaaag gcaagagtgg actgagggta ttttttcctc
tttgcggaaa agcggttgag atgaaatggt ttgcagaccg gggacacagt gtagttggtg
tggaaatcag tgaacttggg atacaagaat tttttacagg gcagaatctt tcttactcag
aagaaccaat caccgaaatt cctggaacca aagtatttaa gagttcttcg gggaacattt
cattgtactg ttgcagtatt tttgatcttc ccaggacaaa tattggcaaa tttgacatga
tttgggatag aggagcatta gttgccatca atccaggtga tcgcaaatgc tatgcagata
caatgttttc cctcctggga aagaagtttc agtatctcct gtgtgttctt tcttatgaac
caactaaaca tccaggtcca ccattttatg ttccacatgc tgaaattgaa aggttgtttg
gtaaaatatg caatatacgt tgtcttgaga aggttgatgc ttttgaagaa cgacataaaa
Maggie
gcgggcggag gcggggcgcg gagaagtggc ggaggtggaa gcggaggcgt acccgcccct
ggggacgtca ttggtggcgg aggcaatggc cggcaaccag ctgtaagcga ggcacggaag
acatatgctt gtgagacaaa ggtgtctctg aaactatgga tggtacaaga acttcacttg
acattgaaga gtactcggat actgaggtac agaaaaacca agtactaact ctggaagaat
ggcaagacaa gtgggtgaac ggcaagactg cttttcatca ggaacaagga catcagctat
taaagaagca tttagatact ttccttaaag gcaagagtgg actgagggta ttttttcctc
tttgcggaaa agcggttgag atgaaatggt ttgcagaccg gggacacagt gtagttggtg
tggaaatcag tgaacttggg atacaagaat tttttacaga gcagaatctt tcttactcag
aagaaccaat caccgaaatt cctggaacca aagtatttaa gagttcttcg gggaacattt
cattgtactg ttgcagtatt tttgatcttc ccaggacaaa tattggcaaa tttgacatga
tttgggatag aggagcatta gttgccatca atccaggtga tcgcaaatgc tatgcagata
caatgttttc cctcctggga aagaagtttc agtatctcct gtgtgttctt tcttatgagc
caactaaaca tccaggtcca ccattttatg ttccacatgc tgaaattgaa aggttgtttg
gtaaaatatg caatatacgt tgtcttgaga aggttgatgc ttttgaagaa cgacataaaa
Jada
gcgggcggag gcggggcgcg gagaagtggc ggaggtggaa gcggaggcgt acccgcccct
ggggacgtca ttggtggcgg aggcaatggc cggcaaccag ctgtaagcga ggcacggaag
acatatgctt gtgagacaaa ggtgtctctg aaactatgga tggtacaaga acttcacttg
acattgaaga gtactcggat actgaggtac agaaaaacca agtactaact ctggaagaat
ggcaagacaa gtgggtgaac ggcaagactg cttttcatca ggaacaagga catcagctat
taaagaagca tttagatact ttccttaaag gcaagagtgg actgagggta ttttttcctc
tttgcggaaa agcggttgag atgaaatggt ttgcagaccg gggacacagt gtagttggtg
tggaaatcag tgaacttggg atacaagaat tttttacagg gcagaatctt tcttactcag
aagaaccaat caccgaaatt cctggaacca aagtatttaa gagttcttcg gggaacattt
cattgtactg ttgcagtatt tttgatcttc ccaggacaaa tattggcaaa tttgacatga
tttgggatag aggagcatta gttgccatca atccaggtga tcgcaaatgc tatgcagata
caatgttttc cctcctggga aagaagtttc agtatctcct gtgtgttctt tcttatgagc
caactaaaca tccaggtcca ccattttatg ttccacatgc tgaaattgaa aggttgtttg
gtaaaatatg caatatacgt tgtcttgaga aggttgatgc ttttgaagaa cgacataaaa
Su
gcgggcggag gcggggcgcg gagaagtggc ggaggtggaa gcggaggcgt acccgcccct
ggggacgtca ttggtggcgg aggcaatggc cggcaaccag ctgtaagcga ggcacggaag
acatatgctt gtgagacaaa ggtgtctctg aaactatgga tggtacaaga acttcacttg
acattgaaga gtactcggat actgaggtac agaaaaacca agtactaact ctggaagaat
ggcaagacaa gtgggtgaac ggcaagactg cttttcatca ggaacaagga catcagctat
taaagaagca tttagatact ttccttaaag gcaagagtgg actgagggta ttttttcctc
tttgcggaaa agcggttgag atgaaatggt ttgcagaccg gggacacagt gtagttggtg
tggaaatcag tgaacttggg atacaagaat tttttacaga gcagaatctt tcttactcag
aagaaccaat caccgaaatt cctggaacca aagtatttaa gagttcttcg gggaacattt
cattgtactg ttgcagtatt tttgatcttc ccaggacaaa tattggcaaa tttgacatga
tttgggatag aggagcatta gttgccatca atccaggtga tcgcaaatgc tatgcagata
caatgttttc cctcctggga aagaagtttc agtatctcct gtgtgttctt tcttatgaac
caactaaaca tccaggtcca ccattttatg ttccacatgc tgaaattgaa aggttgtttg
gtaaaatatg caatatacgt tgtcttgaga aggttgatgc ttttgaagaa cgacataaaa
Nell
gcgggcggag gcggggcgcg gagaagtggc ggaggtggaa gcggaggcgt acccgcccct
ggggacgtca ttggtggcgg aggcaatggc cggcaaccag ctgtaagcga ggcacggaag
acatatgctt gtgagacaaa ggtgtctctg aaactatgga tggtacaaga acttcacttg
acattgaaga gtactcggat actgaggtac agaaaaacca agtactaact ctggaagaat
ggcaagacaa gtgggtgaac ggcaagactg cttttcatca ggaacaagga catcagctat
taaagaagca tttagatact ttccttaaag gcaagagtgg actgagggta ttttttcctc
tttgcggaaa agcggttgag atgaaatggt ttgcagaccg gggacacagt gtagttggtg
tggaaatcag tgaacttggg atacaagaat tttttacaga gcagaatctt tcttactcag
aagaaccaat caccgaaatt cctggaacca aagtatttaa gagttcttcg gggaacattt
cattgtactg ttgcagtatt tttgatcttc ccaggacaaa tattggcaaa tttgacatga
tttgggatag aggagcatta gttgccatca atccaggtga tcgcaaatgc tatgcagata
caatgttttc cctcctggga aagaagtttc agtatctcct gtgtgttctt tcttatgaac
caactaaaca tccaggtcca ccattttatg ttccacatgc tgaaattgaa aggttgtttg
gtaaaatatg caatatacgt tgtcttgaga aggttgatgc ttttgaagaa cgacataaaa
Learning Target:
- I can determine how SNPs in my DNA sequence effect how I can metabolize different drugs that treat cancer.
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.